Registration Dossier
Registration Dossier
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EC number: 202-849-4 | CAS number: 100-41-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Referred in a recognized source of peer reviewed scientific data on chemicals.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Sax's Dangerous Properties of Industrial Materials.
- Author:
- Lewis, R.J.
- Year:
- 1 996
- Bibliographic source:
- 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Handbook data
- Principles of method if other than guideline:
- Handbook data: Acute toxicity; Dermal
- GLP compliance:
- not specified
- Test type:
- other: Handbook data
Test material
- Reference substance name:
- Ethylbenzene
- EC Number:
- 202-849-4
- EC Name:
- Ethylbenzene
- Cas Number:
- 100-41-4
- Molecular formula:
- C8H10
- IUPAC Name:
- ethylbenzene
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Results and discussion
Any other information on results incl. tables
LD50 (rabbits) =17800 mg/kg bw.
Applicant's summary and conclusion
- Conclusions:
- The cut-off value for classification of substances for acute dermal toxicity is LD50= 2000 mg/kg. The published data for ethylbenzene report LD50 values higher than the cut off for classification.
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