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EC number: 202-849-4
CAS number: 100-41-4
It is generally assumed that non-ionised
organic substances with a log Kow below 3 are not significantly
bioaccumulative (refer Section R7c of the ECHA Guidance on information
requirements). Moreover, in the GHS classification system the cut-off
value of log Kow for bioaccumulation is 4. The
estimated log Kow for ethylbenzene is 3.
The Bioconcentration Factor (BCF),
Bioaccumulation factor (BAF) as well as Biotransformation Rate in fish
were estimated by the BCFBAF software using the Arnot-Gobas method. This
method model estimates steady-state BCF (L/kg) and BAF (L/kg) values for
non-ionic organic chemicals in three general trophic levels of fish (i.
e. lower, middle and upper) in temperate environments (default
temperature is 10oC).
Biotransformation Half-Life (normalized
to 10 g fish at 15oC) of 0.35 days was estimated for
ethylbenzene in fish.
Generally, a BCF in fish of ≥ 500 is
indicative of the potential to bioconcentrate for classification
purposes in accordance with CLP/GHS criteria.
The estimated BCF/BAF values of
ethylbenzene in fish (55 -73 L/ kg wet-wt) are well below the cut-off
value of 500 for bioconcentration/ bioaccumulation potential in aquatic
Therefore, ethylbenzene is not likely to
bioaccumulate in aquatic organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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