Registration Dossier
Registration Dossier
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EC number: 201-159-0 | CAS number: 78-93-3
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets generally accepted scientific principles, well-documented publication
Data source
Reference
- Reference Type:
- publication
- Title:
- Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Bakterien (Pseudomonas putida) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest
- Author:
- Bringmann G. & Kuehn R.
- Year:
- 1 977
- Bibliographic source:
- Z Wasser Abwasser Forsch 10(3/4): 87-98
Materials and methods
- Principles of method if other than guideline:
- Cell growth inhibition test: Determination of the biological toxicity of substances hazardous in water to Pseudomonas putida according to Bringmann
- GLP compliance:
- no
Test material
- Reference substance name:
- Butanone
- EC Number:
- 201-159-0
- EC Name:
- Butanone
- Cas Number:
- 78-93-3
- Molecular formula:
- C4H8O
- IUPAC Name:
- butan-2-one
- Details on test material:
- - Name of test material (as cited in study report): Methyläthylketon
- Analytical purity: no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Pseudomonas putida
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 16 h
Test conditions
- Test temperature:
- 25°C
- pH:
- 7
- Details on test conditions:
- - test vessel: 300-mL Erlenmeyer flasks with 100 mL test solution
- measurements: photometric extinction at 436 nm
Results and discussion
Effect concentrations
- Duration:
- 16 h
- Dose descriptor:
- other: TGK
- Effect conc.:
- 1 150 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
