Registration Dossier
Registration Dossier
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EC number: 201-151-7 | CAS number: 78-86-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Two studies on acute toxicity to fish are available, one for zebra fish and one for carp, both being reliable. For hazard and risk assessment the LC50 value determined with zebra fish, being 75.5 mg/l (48 h) is taken forward as a worst case approach.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 75.5 mg/L
Additional information
Acute aquatic toxicity towards fish was tested with zebra fish in a GLP study performed in 1990 (IBR) and was found being harmful to fish showing an LC50 value of 75.5 mg/l (48 h). In another study performed 2002 by Wang et al. with carps a LC50 value (48 h) of 316.22 mg/l was determined, indicating that carps obviously are less sensitive to 2 -Chlorobutane. Consequently, for hazard and risk assessment the value for zebra fish is taken forward.
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