Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 453-230-2
CAS number: 406679-89-8
An acute dermal Irritation/Corrosion test according to OECD 404 was
performed. The test item was semi-occlusively applied to the skin on 3
female New Zealand White Rabbits HsdIf:NZW and held in contact
throughout a 4 hour period. The test item showed slight irritant effects
on the intact skin after a contact time of 4 hours. All animals showed
erythema grade 1 at the 1 h, 24 h, 48 h, 72 h, 96 h, 120 h as well as
144 hours readings after removal of the dressing. No signs of irritation
were recorded for any animals at the 168 hours readings. No other
clinical signs of toxicity were found. There were no significant body
weight changes during the contact and observation period. Therefore, the
test item does not have to be classified and has no obligatory labelling
requirement for skin irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again