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EC number: 453-230-2
CAS number: -
An acute dermal toxicity test according to OECD 402 was performed. The
test item was administered topically at a single dose (2000 mg/kg bw) by
applying uniformly over an area which was approx. 10% of the total body
surface. 5 male animals as well as 5 female animals were used. The test
item was held in contact by an occlusive dressing with the skin
throughout a 24 -hour period. No mortality occured during the study. No
clinical signs of toxicity were observed throughout the observation
period. Weight gain in male animals was within the expected range. For
females slight reduction was found. No macroscopic findings were
observed at necropsy. Therefore, the LD50 (dermal, rat) was determined
to be > 2000 mg/kg bw.
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