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EC number: -
CAS number: -
In order to investigate the potential of VSV16 for its ability to induce
gene mutations the plate incorporation test (experiment I) and the
pre-incubation test (experiment II) were performed with the Salmonella
typhimuriam strains TA 98, TA 100, TA 1535, TA 1537 and TA 102.
In two independent experiments several concentrations of VSV16 were
used. Each assay was conducted with and without metabolic activation.
The concentrations, including the control, were tested in triplicate..
No precipation of VSV16 was observed in any tester strain used in
experiment I and II (with and without metabolc activation).
Toxic effects of VSV16 were noted in all tester strains used in both
No biological relevant increases in revertant colony numbers of any of
the tester strains were observed following the treatment with VSV16 at
any concentration level, neither in presence nor absence of metabolic
acivation in experiment I and II.
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