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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Cross-reference
Reason / purpose for cross-reference:
other:
Reference
Name:
L-arginine phosphate
Type of composition:
legal entity composition of the substance
State / form:
solid: particulate/powder
Reference substance:
L-arginine phosphate

Data source

Referenceopen allclose all

Reference Type:
other company data
Title:
Unnamed
Year:
2019
Reference Type:
study report
Title:
Unnamed
Year:
2020
Report date:
2020

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: DIN ISO 66165-2 particle size analysis - sieving analysis
Version / remarks:
It is applicable to particle sizes up to approximately 125 mm.
GLP compliance:
not specified
Other quality assurance:
other: DIN ISO 66165-2
Type of method:
sieving
Type of particle tested:
primary particle
Type of distribution:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
L-arginine phosphate
EC Number:
949-986-2
Cas Number:
49720-39-0
Molecular formula:
C6H19N4O7P
IUPAC Name:
L-arginine phosphate
Test material form:
solid: crystalline
Remarks:
particulate/powder

Results and discussion

Mass median aerodynamic diameter:
>= 200 - <= 600 µm
Geometric standard deviation:
0
Remarks on result:
other: crystal
Particle sizeopen allclose all
Percentile:
other: granule
Mean:
>= 1 - <= 3 nm
St. dev.:
0
Remarks on result:
other: no data on St.dev
Percentile:
other: crystal
Mean:
>= 200 - <= 600 µm
St. dev.:
0
Remarks on result:
other: no data on St.dev
Key result
Percentile:
D10
Mean:
200 µm
St. dev.:
0
Remarks on result:
other: no data on St.dev
Key result
Percentile:
D50
Mean:
230 µm
St. dev.:
0
Remarks on result:
other: no data on St.dev
Key result
Percentile:
D90
Mean:
360 µm
St. dev.:
0
Remarks on result:
other: no data on St.dev
Particle size distribution at different passagesopen allclose all
No.:
#1
Size:
50 µm
Remarks on result:
other: no data available
No.:
#2
Size:
100 µm
Remarks on result:
other: no data available
No.:
#3
Size:
200 µm
Remarks on result:
other: no data available
No.:
#4
Size:
300 µm
Remarks on result:
other: no data available
No.:
#5
Size:
400 µm
Remarks on result:
other: no data available

Applicant's summary and conclusion

Conclusions:
Particle size distribution is 200 - 600 um for crystal and 1-3 mm for solid granule. With an amplitude of 1.3 mm.
D10 = 200 um
D50 = 230 um
D90 = 360 um