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EC number: 949-957-4
CAS number: -
objective of this study was to determine the effect of the test item on
the immobilization of Daphnia magna.
daphnids were exposed to a nominal test item concentration of 100 mg/L
(limit test) in an open static system. 20 daphnids, divided into four
replicates, each with five animals were used in the test item group and
the control group. The daphnids were observed for immobilization after
24 and 48 hours of exposure.
test item concentration in the reconstituted water was not quantified at
the start and the end of this study. Because of the low water solubility
(1.663x10 -14 mg/L), the compound cannot be detected with
standard analytical methods and the development of an analytical method
with a sufficiently low detection and quantification limit is complex.
Due to the absence of any
adverse effects at the saturation concentration, the study was performed
without analytical concentration verification.
No effect on the mobility of
the daphnia was observed at a nominal concentration of 100 mg/L.
the test item the following EC50 values were determined:
100 mg/L (nominal): >1.663
mg/L (nominal): >1.663
Under the conditions of the present study, an aqueous solution of
nominal 100 mg/L of the test item revealed no toxicity to daphnids. The
48h EC50 was >1.663
(nominal > 100 mg/L) and, thus, could not be determined.
This study was performed according
to GLP and the methods applied are fully compliant with OECD TG 202. No
adverse effects on daphnia were observed up to the water solubility of
the test.The 48h EC50 was >1.663
× 10-14mg/L (nominal >100 mg/L) and, thus, could
not be determined in this study.
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