Registration Dossier
Registration Dossier
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EC number: 947-918-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental data on the toxicity of Reaction product of 1,3,5-Triazine-2,4,6-triamine, polymer with formaldehyde, methylated and C16-18 fatty alcohols are available for the following endpoints: Short-term toxicity to fish, toxicity to algae and toxicity to microorganisms. All studies were conducted under GLP. Short-term toxicity testing on aquatic invertebrates was deemed not necessary since a long-term toxicity study is proposed to be conducted due to the poor water solubility of the test substance (< 15 µg/L at 20 °C and pH 6.3; OECD 105). In a study conducted according to OECD 203, which investigated the short-term toxicity of the substance to fish, no lethal or sublethal effects on fish were observed. The LL50/LC50 (96 h) of the test item was determined as > 100 mg/L (nominal) and > 3.16 mg/L (geometric mean measured), respectively. The corresponding NOELR/NOEC (mortality) (96 h) was 100 mg/L (nominal) and 3.16 mg/L (geometric mean measured), respectively. In a study conducted according to OECD 201 which investigated the toxicity of the test substance to aquatic algae, the substance showed no toxicity up to the highest tested nominal loading rate (100 mg/L). The ErL50 and ErL10 was determined as > 100 mg/L and ≥ 100 mg/L (nominal). In a key study conducted according to OECD 209, which investigated the toxicity of the test substance to microorganisms, the substance showed no inhibition up to the highest tested concentration (1000 mg/L). An EC50 (3h) of > 1000 mg/L (respiration inhibition) was determined. Supporting information from the ready biodegradability study conducted according to the OECD guideline 301B (CO2 evolution), showed that the test item had no inhibitory effect on activated sludge microorganisms (34 % biodegradation within 14 days).
Based on the available results from experimental data onReaction product of 1,3,5-Triazine-2,4,6-triamine, polymer with formaldehyde, methylated and C16-18 fatty alcohols,it can be concluded that the test substance is not toxic to aquatic organisms up to the limit of water solubility(< 15 µg/L at 20 °C and pH 6.3; OECD 105).
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