Registration Dossier
Registration Dossier
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EC number: 201-145-4 | CAS number: 78-81-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- NOAEC
- 500 mg/m³
- Study duration:
- subchronic
- Species:
- rat
- Quality of whole database:
- 1
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
The NOAEC for systemic toxicity was 500 mg/m3 in the 90-day inhalation toxicity study. Because the Guidance Value Range to assist in potential STOT RE classification (specific target organ toxicity repeated exposure) is 10 - 100 mg/kg/day for the inhalation route of exposure, no classification is justified for the substance according to the CLP Regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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