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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06-12-2010 to 16-12-2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study performed under GLP. All relevant validity criteria were met.
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
inspected: May 2009; signature: July 2009
Type of method:
flask method
Water solubility:
604.55 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
4
Remarks on result:
other: Determination of A/B/C: Equilibrated at 20°C 24 hours
Water solubility:
568.97 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
4
Remarks on result:
other: Determination of A/B/C: Equilibrated at 20°C 48 hours
Water solubility:
568.14 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
4
Remarks on result:
other: Determination of A/B/C: Equilibrated at 20°C 72 hours
Water solubility:
581 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
4
Remarks on result:
other: Mean concentration: 581 mg/L at 20.0 ± 0.5°C
Conclusions:
Interpretation of results: moderately soluble (100-1000 mg/L)
The water solubility was determined to be 581 mg/L of solution at 20.0 ± 0.5 °C.
Executive summary:

The water solubility of the test item was determined using the flask method according to EU Method A.6 and OECD Method 105 under GLP. The water solubility was determined to be 581 mg/L of solution at 20.0 ± 0.5 °C.

Description of key information

Water Solubility: 581 mg/L at 20 ± 0.5 °C, EU Method A.6 – flask method, 2010

Key value for chemical safety assessment

Water solubility:
581 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the test item was determined using the flask method according to EU Method A.6 and OECD Method 105 under GLP. The water solubility was determined to be 581 mg/L of solution at 20.0 ± 0.5 °C.