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EC number: 695-797-0
CAS number: 93601-86-6
Summary of opacity, permeability and in
Mean in vitro irritation score
Individual in vitro irritancy scores:
In vitro Irritancy Score
pH effect of the test substance was observed on the rinsing medium.
the Bovine Corneal Opacity and Permeability test (BCOP test) the
substance was screened for its eye irritancy potential in accordance
with OECD 437 and according to GLP principles. Since no workable
suspension in physiological saline could be obtained, the substance was
applied as such directly on top of the corneas in such a way that the
cornea was completely covered (312 to 318 mg per cornea). Adequate
negative and positive controls were included. The substance did not
induce ocular irritation, resulting in a mean in vitro irritancy score
of 1.6 after 240 minutes of treatment. Since the substance induced a
mean IVIS ≤ 3, the substance does not need to be classified for Eye
irritation/corrosion in accordance with the CLP Regulation.
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