Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 241-026-4
CAS number: 16957-70-3
A Corrositex assay was performed, equivalent to OECD guideline 435
and non-GLP, to assess the substance's potential to be corrosive to the
skin. Prior to the start of the corrosivity testing, a qualification
screening and a pH screening were performed to determine whether the
substance could be analyzed in this system. The substance induced an
immediate color change in the Chemical Detection System (CDS)
qualification tube and the pH of the substance was 2.5. Membrane discs
were prepared by adding a scintillation vial to a biobarrier matrix
powder. In the corrosivity study, 500 µL of the substance was applied to
membrane discs which were placed into a vial containing the CDS. A
positive control of NaOH and a negative (blank) control were included.
The substance did not induce a distinct color change from the biobarrier
matrix within the CDS. Therefore, no precise break through time could be
determined. However, it was clear from the results that a break through,
indicative of a corrosive response, was detected in all four vials prior
to the 3 hour and 30 minutes observation, and at approximately 3 hours.
The validity of the test system was shown by the results of the positive
control which fell within the historical range and the results of the
negative control, which did not induce a colour change. Based on this
result, the substance is classified as corrosive to the skin, category
1C according to Regulation (EC) No. 1272/2008 and its amendments.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again