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EC number: 241-026-4
CAS number: 16957-70-3
In a valid guideline study, the 48 hour EC50 for Daphnia magna was >130
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The short-term toxicity to aquatic invertebrates is assessed based on
read-across from the close structural analogue Methacrylic acid (CAS# 79
-41 -4). The data of Methacrylic acid are summarised below.
For Methacrylic acid, the short-term toxicity to daphnids was examined
in a study according to EAP OTS 797-1300 (equivalent to OECD TG 202),
and in compliance with GLP criteria (MPA, 1990). Groups of 40 Daphnia
magna (4 replicates of 10 animals) were exposed to nominal test
substance concentrations 0 (control), 7.2, 14, 30, 60 and 120 mg/L for
48 hours under flow-through conditions. Test substance analysis was
performed and mean measured concentrations determined at 6.7, 13, 32, 62
and 130 mg/L. Daphnia mobility was recorded. The 48-h EC50 was
determined at >130 mg/L based on mean measured concentrations.
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