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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
publication
Title:
Risk assessment in immunotoxicology: Sensitivity and predictability of immune tests
Author:
Luster, M.I., Portier, C., Pait, D.G., White, K.L., Gennings, C., Munson, A.E., Rosenthal, G.J.
Year:
1992
Bibliographic source:
Fundamental Applied Toxicology Vol 18, pp 200-210

Materials and methods

Type of study / information:
Type: other: Hypersensitization
Principles of method if other than guideline:
No method cited

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetraethyllead
EC Number:
201-075-4
EC Name:
Tetraethyllead
Cas Number:
78-00-2
Molecular formula:
C8H20Pb
IUPAC Name:
tetraethylplumbane
Details on test material:
TS-Freetext:
Tetraethyl lead (TEL).

Results and discussion

Applicant's summary and conclusion

Conclusions:
When TEL was administered in three different concentrations to test animals, over 14 days via stomach tube, hypersensitization and a raised leucocyte count were detected
Executive summary:

When TEL was administered in three different concentrations to test animals, over 14 days via stomach tube, hypersensitization and a raised leucocyte count were detected