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Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 29-30, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes
Type of method:
other: slow-stir method

Test material

Constituent 1
Test material form:
solid: flakes
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Mitsubishi-Chemical Foods Corporation; 63281211
- Expiration date of the lot/batch: March 27, 2018
- Purity test date: June 23, 2017

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Final preparation of a solid: dissolved in reagent water

FORM AS APPLIED IN THE TEST (if different from that of starting material): solution

Results and discussion

Water solubility
Key result
Water solubility:
5.97 mg/L
Conc. based on:
other: Total organic carbon
Loading of aqueous phase:
0.1 other: mg/mL
Incubation duration:
24 h
Temp.:
20 °C
pH:
>= 6.23 - <= 6.42
Details on results:
Results ranged from 5.57 mg/L to 6.37 mg/L, a difference of 13%.

Applicant's summary and conclusion

Conclusions:
The mean water solubility was 5.97 +/- 2.3 mg/L.
Executive summary:

The water solubility of LMDT was determined using the slow-stir method. The test substance was placed in water and stirred for 24 hrs, and allowed to equilibrate for 1 hr. Triplicate samples were then analyzed using TOC analysis. Three additional samples were taken at 48 hrs. The mean water solubility at 20 degrees C was 5.97 +/- 2.3 mg/L.