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EC number: -
CAS number: -
In an in vivo skin irritation study performed according to OECD/EC guideline and GLP principles, the substance was not irritating.In an in vivo eye irritation study performed according to OECD/EC guideline and GLP principles, the substance was not irritating.
In an in vitro skin corrosion test performed according to OECD 431 and
GLP principles, the substance was not corrosive. In the subsequently
performed in vivo skin irritation test in rabbits performed according to
OECD 404 and GLP principles, the substance was not irritating.
In the Bovine Corneal Opacity and Permeability test performed according
to OECD/EC guideline, the substance showed a mean irritancy score of 0.1
after 240 minutes of treatment, which means the substance is not an
ocular irritant in this test. In the subsequently performed in vivo eye
irritation test in rabbits performed according to OECD/EC guideline,
instillation of the substance in the eye resulted in irritation of the
conjunctivae, which consisted of redness, chemosis and discharge. The
irritation has completely resolved within 48 hours and the substance was
considered to be slightly irritating to the eyes.
Based on these results the substance does not have to be classified and
has no obligatory labelling requirement for skin and eye irritation
according to the:
- Globally Harmonized System of Classification and Labelling of
Chemicals (GHS) of the United Nations (2011),
- Regulation (EC) No 1272/2008 on classification, labelling and
packaging of substances and mixtures.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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