Registration Dossier
Registration Dossier
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EC number: 219-983-4 | CAS number: 2591-76-6
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The test substance has a log Pow of 1.9 at 25 °C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.9
- at the temperature of:
- 25 °C
Additional information
The available data were evaluated in a weight of evidence approach. In a BASF study (1988) a log Pow of 1.9 at 25 °C was determined. Furthermore, the GESTIS database states a log Pow of 1.09. In addition, the log Pow was calculated using EPISuite v.4.11 KOWWIN. The log Pow was calculated to be 1.87 at 25 °C. All values were in the same range. The BASF study was regarded as the most reliable source. Thus, the log Pow of 1.9 was chosen as key value.
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that
information on intrinsic properties of substances may be generated by
means other than tests, provided that the conditions set out in Annex XI
(of the same Regulation) are met. Furthermore according to Article 25 of
the same Regulation testing on vertebrate animals shall be undertaken
only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can
be used if (1) the scientific validity of the (Q)SAR model has been
established, (2) the substance falls within the applicability domain of
the (Q)SAR model, (3) the results are adequate for the purpose of
classification and labeling and/or risk assessment and (4) adequate and
reliable documentation of the applied method is provided.
For the assessment of N,N-diisobutylformamide (Q)SAR results were used
for partition coefficient. The criteria listed in Annex XI of Regulation
(EC) No 1907/2006 are considered to be adequately fulfilled and
therefore the endpoint(s) sufficiently covered and suitable for risk
assessment.
Therefore, further experimental studies on partition coefficient are not
provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
