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EC number: 943-097-3
CAS number: -
Individual Body Weights and Clinical Observations
Body weight (g)
Body weight change (g)
Eye Irritation Scores at Observation Point on Treated Eye
= (Degree of density/Area of opacity)
red colored iris
using the procedures outlined in the QPS Taiwan Study Plan for
T65316006-IR which is based on the SOP for the OECD 405 (CTPS-TE00441)
and OECD 405 (OECD, 2012). CJ313
was given by a single ocular application at 0.1 g amount to NZW
female rabbits and followed by ocular examination and clinical
more than 21 days. There were no test article effects on body weight. No
irritation reaction in cornea and iris. Reversible conjunctiva redness
and chemosis were observed within 24 hoursafter
test article application. On
the basis of the test results given above, the response of the test
article was judged as a positive irritant to the eye.
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