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Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental Starting Date 04/28/2015 and Experimental Completion 04/30/2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Specific details on test material used for the study:
Identification: FAT 20036/G TE Lot. MH-0033439900
Appearance: Blue powder
Water solubility:
53.7 g/L
Temp.:
20 °C
Remarks on result:
other: pH is not known
Details on results:
None

Preliminary Visual Estimation of the Water Solubility

Appearance of the test mixtures in the preliminary test.

 Amount of the test item in mg Total volume in ml  Appearance of mixture 
 100  1.0  Undissolved
 100  2.5  Dissolved
 100  5.0  Dissolved

The preliminary visual experiments showed that the water solubility of the test item is about 40 g/l.

Flask-Method

Water solubility of the test item – experiments A to D.

Experiment

A

B

C

D(blank)

Amount of test item(mg)

1000

1000

1000

---

Stirring time at 30 °C (h)

24

48

72

72

Measured concentration (μg/ml)

6.51

6.87

6.74

---

Aliquot

0.025/10/0.5/10

0.025/10/0.5/10

0.025/10/0.5/10

0.025/10/0.5/10

Water solubility (g/l)

52.1

55.0

53.9

---

Average experiments A to C: 53.7 g/L

Standard addition for recheck :

Standard

Measured concentration

(mg/l)

% Recovery

Sample C + 10.0 μg test item

16.9

102.4

The recovery of 102.4 % indicates a sufficient accuracy of the analytical method.

Conclusions:
The water solubility of the test item at a temperature of 20 °C was determined to be 53.7 g/L.
Executive summary:

The water solubility of FAT 20036/G TE was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used fot this purpose. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 53.7 g/L.

Description of key information

The water solubility of FAT 20036/G TE was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used fot this purpose. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 53.7 g/L.

Key value for chemical safety assessment

Water solubility:
53.7 g/L
at the temperature of:
20 °C

Additional information