Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
GLP compliance:
yes (incl. QA statement)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Gelb LD 6259
- Analytical purity: 61.3 g per 100 g
- Lot/batch No.: 0817VP01

Study design

Buffers:
- pH: 4, 7, 9
- Composition of buffer: pH 4 (Bernd Kraft, citric acid, sodium chloride, sodium hydroxide), pH 7 (Bernd Kraft, phosphate mixture), pH 9 (Bernd Kraft, boric acid, sodium hydroxide, potassium chloride), acetonitrile, dipotassium hydrogenphosphate, PIC A reagent (tetrabutylammonium hydroxide waters)

Results and discussion

Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
50 °C
Remarks on result:
other: no hydrolysis observed (<10 % within 5 days)
pH:
7
Temp.:
50 °C
Remarks on result:
other: no hydrolysis observed (<10 % within 5 days)
pH:
9
Temp.:
50 °C
Hydrolysis rate constant:
0.01 h-1
DT50:
68.3 h

Applicant's summary and conclusion