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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment. Toxicity report giving very brief summary of this and other studies.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1972
Report date:
1972

Materials and methods

Principles of method if other than guideline:
No guideline mentioned. Similar to Inhalation Hazard Test described as an Annex to OECD 403. Exposure to atmosphere said to be saturated with vapour for 7 h.
GLP compliance:
no
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
Triethoxy(vinyl)silane
EC Number:
201-081-7
EC Name:
Triethoxy(vinyl)silane
Cas Number:
78-08-0
Molecular formula:
C8H18O3Si
IUPAC Name:
triethoxy(vinyl)silane

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
other: unchanged (no vehicle)
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
7 h
Concentrations:
Exposure to saturated atmosphere at room temperature (not further specified), said to be approx. 2300 ppm vapour.
No. of animals per sex per dose:
Not stated
Control animals:
not specified

Results and discussion

Effect levelsopen allclose all
Sex:
not specified
Dose descriptor:
LC0
Effect level:
> 2 300 ppm
Based on:
other: saturated vapour
Exp. duration:
7 h
Sex:
not specified
Dose descriptor:
LC50
Effect level:
> 2 300 ppm
Based on:
other: saturated vapour
Exp. duration:
7 h
Sex:
not specified
Dose descriptor:
LC0
Effect level:
> 17 876 mg/m³ air
Based on:
other: a molecular weight of 190.3 g/mol at 25°C
Exp. duration:
7 h
Sex:
not specified
Dose descriptor:
LC50
Effect level:
> 17 876 mg/m³ air
Based on:
other: a molecular weight of 190.3 g/mol at 25°C
Exp. duration:
7 h

Any other information on results incl. tables

No deaths reported. No details of observation period, if any. Moderate diureses reported in an unstated number but no other observations.

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
A very limited summary of an unspecified study, without guideline or GLP compliance (reliability score 4), recorded no deaths in rats from exposure to approx. 2300 ppm vapour. (This reviewer notes this value to be equivalent to around 17876 mg/m³ at 25°C, based on a molecular weight of 190.3 g/mol)