Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-077-3 | CAS number: 7785-26-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Study performed similarly to OECD guideline 117 with data scientifically acceptable but not performed under GLP
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- no
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.48
- Temp.:
- 37 °C
- pH:
- 7.2
- Remarks on result:
- other: standard error: 0.06
- Details on results:
- - Experimental log Kow (RP-HPLC) = 4.48 (S.E.: 0.06) at 37 °C
- Calculated log Kow = 4.34 (fragment method), 4.27 (atom /fragment contribution method) and 2.80 (atomistic method) - Conclusions:
- The partition coefficient, log Kow, of (-)-alpha-pinene was determined as 4.48 (S.E. = 0.06) at 37 °C.
Calculated log Kow values of (-)-alpha-pinene were also reported : 4.34 (fragment method), 4.27 (atom /fragment contribution method) and 2.80 (atomistic method). - Executive summary:
A study was conducted to determine the partition coefficient of (-)-α-pinene by Reverse Phase High Performance Liquid Chromatographic method similarly to OECD Guideline 117.
The partition coefficient, log Kow, of (-)-alpha-pinene was determined as 4.48 (S.E. = 0.06) at 37 °C.
Calculated log Kow values of (-)-alpha-pinene were also reported : 4.34 (fragment method), 4.27 (atom /fragment contribution method) and 2.80 (atomistic method).
Reference
None
Description of key information
The partition coefficient, log Kow, of (-)-alpha-pinene was determined as 4.48 (S.E. = 0.06) at 37 °C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.48
- at the temperature of:
- 37 °C
Additional information
A study was conducted according to Guideline OECD 117 to measure the partition coefficient of (-)-alpha-pinene.
The value was considered with a reliability of 2 (reliable with restrictions) because the result is scientifically acceptable but not obtained under GLP and some details were lacking in the report.
This result is supported by consistent experimental data obtained with alpha-pinene multiconstituent.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
