Registration Dossier
Registration Dossier
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EC number: 219-668-1 | CAS number: 2494-88-4
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Danish (Q)SAR Database
- Title:
- Danish (Q)SAR Study for 2494-88-4
- Year:
- 2 012
- Bibliographic source:
- Commercial
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Ames mutagenicity. Multicase model.
- GLP compliance:
- no
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- 2-[(3-aminophenyl)sulphonyl] hydrogensulphate
- EC Number:
- 219-668-1
- EC Name:
- 2-[(3-aminophenyl)sulphonyl] hydrogensulphate
- Cas Number:
- 2494-88-4
- Molecular formula:
- C8H11NO6S2
- IUPAC Name:
- [2-(3-aminobenzenesulfonyl)ethoxy]sulfonic acid
Constituent 1
Results and discussion
Test results
- Species / strain:
- other: Salmonella
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- no cytotoxicity
- Vehicle controls validity:
- not specified
- Untreated negative controls validity:
- not specified
- Positive controls validity:
- not specified
- Remarks on result:
- other: all strains/cell types tested
- Remarks:
- Migrated from field 'Test system'.
Applicant's summary and conclusion
- Conclusions:
- AMES test of the substance to Salmonella is negative.
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