Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-304-8
CAS number: 80-73-9
Short term toxicity to fish
In a 96 -h acute toxicity study, Ricefish (Oryzias latipes) (5/group)
were exposed to the substance at a nominal concentration of 100 mg/L
under semi-static conditions (Biotoxtech 2013, report J12480). There
were no mortalities or other adverse reactions to exposure in the
exposed fish. The 96 -h LC50 and NOEC values were higher than 100
mg/L, based on mortality. The toxicity study is classified as
acceptable and fully satisfies the guideline requirement for
short-term toxicity to fish.
Long term toxicity to fish
The study is proposed to be waived.
Short-term toxicity to aquatic invertebrates
The 48–h-acute toxicity of the substance to daphnia magna was
studied under static conditions (Safepharm 1998, report 458/176).
Daphnids were exposed to control and test chemical at a nominal
concentration of 100 mg/L for 48h. Mortality/immobilization and
sublethal effects were observed daily and at test termination.
The 24h-NOEC and 48h-NOEC based on immobilization were both
greater or equal to100 mg/L. The EC50 in the daphnia magna
immobilisation test is greater than 100mg/L. This study is
classified as acceptable and satisfies the guideline requirements
for an acute toxicity study with freshwater invertebrates.
Long-term toxicity to aquatic invertebrates
This study is proposed to be waived.
Toxicity to aquatic algae and cyanobacteria
An algal growth inhibition test was conducted by
Safepharm Laboratories Limited, to determine the
effect of the test substance on the aquatic
environment. The study was conducted in
compliance with GLP, and was performed according
to EC test guideline C3 (Safepharm 1998, report
number 458/175). The biomass increase and growth
rate of a culture of algae (scenedesmus
subspicatus) was monitored over a period of
72 hours in growth media containing test
substance at a concentration of 100 mg/L. The 72
the test substance with algae was determined to
be greater than 100 mg/L.
Toxicity to aquatic plants other than algae
No data available. No data required.
Toxicity to microorganisms
The effect of the substance on the respiration
rate of activated sludge was assessed by the
methods detailed in and OECD Test Guideline 209
and in compliance with GLP (HLS 2013,
not significantly inhibit the respiration rates
of the samples of activated sludge. The
three-hour EC50 must therefore be >1000 mg/L.
The no observed effect concentration was greater
1000 mg/L, the highest concentration tested.
Toxicity to other microorganisms
No data available. No data required.
The substance is not toxic in the aquatic
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again