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EC number: 931-607-7
CAS number: -
specific information for the UVCB substance "Lead bullion, Platinum
Group metals rich" is not available for the endpoint “toxicokinetics”.
However, there is no specific requirement to generate toxicokinetic data
under Regulation (EC) 1907/2006 (REACH). Annex I, Section 1.0.2 of REACH
regulation states that “the human health hazard assessment
shall consider the toxicokinetic profile (i.e. absorption, metabolism,
distribution and elimination) of the substance” and REACH regulation
announces in Annex VIII, Section 8.8.1 that one should perform “assessment
of the toxicokinetic behaviour of the substance to the extent that can
be derived from the relevant available information”.
"Lead bullion, Platinum Group metals rich", the human health (HH) hazard
assessment is driven by the hazard assessment of the individual UVCB
constituents which are (i) classified for HH and (ii) with a content ≥
0.1 %. For most of the relevant constituents, toxicokinetic data are
fully assessed and included in each individual REACH registration file
but have not been included in the registration file of "Lead bullion,
Platinum Group metals" rich (see strategy of registration for UVCB
substances – Precious Metals Refinables). Relevant hazard and risk
assessment information for "Lead bullion, Platinum Group metals rich"
can be found in IUCLID Section 7 “Toxicological information_ Lead
bullion, Platinum Group metals rich”.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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