Registrované látky

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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Je zobrazeno 501 - 600 položek z celkového počtu 26 542.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	Active	Full	Joint	≥ 1 to < 10 tonnes	11-06-2020	View substance registered dossier
(4aR,8aR)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one	428-690-2	1668-86-6	Cease Manufacture	NONS	Individual	Cease manufacture	23-11-2010	View substance registered dossier
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one	680-670-4	13649-88-2	Active	Intermediate	Joint	Intermediate use only	10-08-2021	View substance registered dossier
(4aS-cis-)-6-benzyl-octahydropyrrolo[3.4-b]pyridine	425-930-8	151213-39-7	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(4E)-2,4-dimethyl-5-(4-methylphenyl)pent-4-enal	951-965-8	1226911-73-4	Active	Full	Joint	≥ 1 to < 10 tonnes	07-12-2021	View substance registered dossier
(4E)-4-(3,3,4-trimethylcyclopentylidene)butanal	953-704-3	2411191-47-2	Active	Full	Joint	≥ 0 to < 10 tonnes	05-03-2021	View substance registered dossier
(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one	941-406-6	1391712-50-7	Active	Intermediate	Joint	Intermediate use only	08-01-2019	View substance registered dossier
(4E)-4-METHYL-5-(4-METHYLPHENYL)-4-PENTENAL	700-748-4	1226911-69-8	Active	Full	Joint	≥ 0 to < 10 tonnes	20-12-2017	View substance registered dossier
(4E)-5-cyclohexyl-2,4-dimethylpent-4-enal	947-579-4	1449104-34-0	Active	Full	Joint	≥ 1 to < 10 tonnes	08-12-2020	View substance registered dossier
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid	849-166-3	83841-00-3	Active	Intermediate	Joint	Intermediate use only	18-05-2021	View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine	926-346-0	-	Active	Intermediate	Joint	Intermediate use only	10-11-2017	View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one (R)-1,2-PROPYLENE CARBONATE	437-320-9	16606-55-6	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	Active	Full	Joint	≥ 1 to < 10 tonnes	18-08-2020	View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	Cease Manufacture	NONS	Individual	Cease manufacture	10-11-2008	View substance registered dossier
(4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide	809-887-6	1206102-11-5	Active	Intermediate	Individual	Intermediate use only	27-06-2019	View substance registered dossier
(4R,4'S)-[4,4'-bi-1,3-dioxolane]-2,2'-dione	636-728-6	24690-44-6	Active	Full	Joint	≥ 1 to < 10 tonnes	22-12-2021	View substance registered dossier
(4R,4aS,7aR,12bS)-3-(ethoxycarbonyl)-7-oxo-1,2,3,4,7,7a-hexahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate	955-282-6	2387639-94-1	Active	Intermediate	Joint	Intermediate use only	15-12-2021	View substance registered dossier
(4R,4aS,7aR,12bS)-3-methyl-7-oxo-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate	875-213-2	50798-31-7	Active	Intermediate	Joint	Intermediate use only	03-11-2021	View substance registered dossier
(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol	604-572-8	147128-77-6	Active	Intermediate	Joint	Intermediate use only	06-09-2018	View substance registered dossier
(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene	610-461-5	495-61-4	Active	Full	Individual	≥ 1 to < 10 tonnes	23-02-2022	View substance registered dossier
(4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one	700-586-4	852212-81-8	Active	Intermediate	Individual	Intermediate use only	10-05-2011	View substance registered dossier
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone	848-798-7	272778-12-8	Active	Intermediate	Joint	Intermediate use only	15-06-2020	View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate	947-346-7	-	Active	Intermediate	Individual	Intermediate use only	22-10-2021	View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide	623-314-5	98674-86-3	Active	Intermediate	Joint	Intermediate use only	26-03-2018	View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	No longer Valid	Intermediate	Individual	No longer valid	29-05-2018	View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	Active	Intermediate	Joint	Intermediate use only	23-03-2022	View substance registered dossier
(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)	825-705-8	1235460-56-6	Active	Intermediate	Joint	Intermediate use only	17-07-2018	View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)	940-053-5	-	Active	Intermediate	Joint	Intermediate use only	19-01-2017	View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	Active	Intermediate	Joint	Intermediate use only	13-09-2018	View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	811-441-0	1035654-66-0	Active	Intermediate	Joint	Intermediate use only	27-11-2019	View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride	611-780-2	59046-78-5	Active	Intermediate	Individual	Intermediate use only	14-05-2018	View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid	618-775-4	916439-93-5	Active	Intermediate	Joint	Intermediate use only	22-12-2017	View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate	947-931-7	-	Active	Intermediate	Individual	Intermediate use only	24-05-2018	View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)	925-915-0	-	Active	Intermediate	Individual	Intermediate use only	24-05-2018	View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid HYDROXYECTOIN	442-870-8	165542-15-4	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,	824-717-0	403848-30-6	Active	Intermediate	Joint	Intermediate use only	05-06-2018	View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide	947-800-4	-	Active	Intermediate	Joint	Intermediate use only	21-06-2018	View substance registered dossier
(4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid MDL 28,690	443-440-2	150379-92-3	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide	604-558-1	147086-83-7	Active	Intermediate	Joint	Intermediate use only	09-03-2018	View substance registered dossier
(4Z)-hept-4-en-2-yl salicylate	700-488-1	873888-84-7	Active	Full	Individual	≥ 1 to < 10 tonnes	09-11-2010	View substance registered dossier
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid	700-141-4	117570-53-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	22-06-2010	View substance registered dossier
(5-bromothiophen-2-yl)-phenylmethanone	608-584-4	31161-46-3	Active	Intermediate	Joint	Intermediate use only	14-02-2018	View substance registered dossier
(5-chloro-2-methoxyphenyl)boronic acid	923-256-3	-	Active	Intermediate	Individual	Intermediate use only	27-04-2018	View substance registered dossier
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	02-12-2021	View substance registered dossier
(5E)-3,5-dimethyloct-5-en-4-ol	947-581-5	2209852-19-5	Active	Full	Joint	≥ 1 to < 10 tonnes	13-03-2020	View substance registered dossier
(5or8)-aminonaphthalene-2-sulphonic acid	257-269-4	51548-48-2	Active	Full	Joint	≥ 1 to < 10 tonnes	06-04-2018	View substance registered dossier
(5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate	820-260-6	93603-76-0	Active	Intermediate	Joint	Intermediate use only	28-06-2018	View substance registered dossier
(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose	815-962-4	1384242-56-1	Active	Intermediate	Joint	Intermediate use only	04-12-2019	View substance registered dossier
(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol	879-204-4	1373116-05-2	Active	Intermediate	Joint	Intermediate use only	04-02-2022	View substance registered dossier
(5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride	874-683-6	1373116-04-1	Active	Intermediate	Joint	Intermediate use only	15-10-2021	View substance registered dossier
(5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one	821-898-8	39931-87-8	Active	Intermediate	Joint	Intermediate use only	07-05-2020	View substance registered dossier
(5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one	260-887-7	57664-96-7	Active	Intermediate	Joint	Intermediate use only	28-04-2017	View substance registered dossier
(5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate	264-989-2	64643-76-1	Active	Intermediate	Individual	Intermediate use only	03-12-2018	View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	Active	Intermediate	Joint	Intermediate use only	31-03-2022	View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride	257-924-4	52446-24-9	Active	Intermediate	Joint	Intermediate use only	16-03-2017	View substance registered dossier
(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol	207-385-6	467-04-9	Active	Intermediate	Joint	Intermediate use only	29-06-2022	View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one	208-085-8	508-54-3	No longer Valid	Intermediate	Joint	No longer valid	15-03-2018	View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one	282-186-5	84116-46-1	No longer Valid	Intermediate	Joint	No longer valid	12-07-2019	View substance registered dossier
(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride	245-549-9	23277-43-2	Active	Intermediate	Joint	Intermediate use only	19-06-2017	View substance registered dossier
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 2691; CARTASOL BRILLANT SCHARLACH K-2GL KONZ.; CARTASOL BRILLANTSCHARLACH K-2GL FLÜSSIG (ZUBEREITUNG); CARTASOL BRILLANTSCHARLACH K-2GL GRANULAT (ZUBEREITUNG); CARTASOL BRILLIANT SCARLET K-2GL; CARTASOL BRILLIANT SCARLET K-2GL CONC.	402-060-7	108225-03-2	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride	842-055-0	2356133-42-9	Active	Intermediate	Individual	Intermediate use only	21-08-2019	View substance registered dossier
(6-aminohexyl)carbamic acid	205-581-6	143-06-6	Active	Full	Joint	≥ 100 to < 1 000 tonnes	02-10-2018	View substance registered dossier
(6-Bromo-2-pyridinyl)(4-methylphenyl)methanone	618-079-0	87848-95-1	No longer Valid	Full	Individual	No longer valid	25-10-2019	View substance registered dossier
(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate	938-716-9	-	No longer Valid	Intermediate	Individual	No longer valid	04-02-2013	View substance registered dossier
(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one	603-081-6	125-58-6	Active	Intermediate	Joint	Intermediate use only	22-09-2017	View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	Active	Intermediate	Individual	Intermediate use only	18-12-2013	View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	24-11-2014	View substance registered dossier
(6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	617-560-2	84377-83-3	No longer Valid	Full	Joint	No longer valid	15-11-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride	827-945-9	107648-80-6	Active	Intermediate	Joint	Intermediate use only	21-09-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide	606-382-0	197897-11-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	20-04-2018	View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	700-301-3	69739-16-8	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-06-2009	View substance registered dossier
(6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine	605-428-7	16614-59-8	Active	Intermediate	Joint	Intermediate use only	18-12-2020	View substance registered dossier
(6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide	423-260-0	100988-63-4	Cease Manufacture	NONS	Individual	Cease manufacture	29-10-2012	View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	Active	Intermediate	Joint	Intermediate use only	19-12-2018	View substance registered dossier
(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid TACS	403-690-5	111298-82-9	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	250-099-1	30246-33-4	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	258-907-4	53994-69-7	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	Active	Intermediate	Joint	Intermediate use only	16-12-2019	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Cease Manufacture	Full	Joint	Cease manufacture	03-05-2018	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Active	Intermediate	Joint	Intermediate use only	10-07-2019	View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one	-	-	Active	Intermediate	Joint	Intermediate use only	14-03-2022	View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate	949-377-1	-	Active	Intermediate	Joint	Intermediate use only	10-05-2019	View substance registered dossier
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	Active	Full	Joint	≥ 1 to < 10 tonnes	26-11-2020	View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	Active	Intermediate	Joint	Intermediate use only	13-11-2017	View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	Active	Full	Joint	≥ 1 to < 10 tonnes	17-12-2020	View substance registered dossier
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one	615-123-0	7055-53-0	Active	Intermediate	Joint	Intermediate use only	28-01-2022	View substance registered dossier
(6β)-6,19-epoxyandrost-4-ene-3,17-dione	433-490-3	6563-83-3	Active	NONS	Individual	Tonnage data confidential	15-12-2008	View substance registered dossier
(7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate	807-380-4	377734-55-9	No longer Valid	Full	Joint	No longer valid	26-03-2018	View substance registered dossier
(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	Active	Full	Joint	≥ 1 to < 10 tonnes	11-05-2018	View substance registered dossier
(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	Active	Full	Joint	≥ 1 to < 10 tonnes	01-10-2018	View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	642-947-8	415927-29-6	Active	Intermediate	Individual	Intermediate use only	04-04-2018	View substance registered dossier
(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthrene-3,17-diol	642-948-3	153004-31-0	Active	Intermediate	Joint	Intermediate use only	30-11-2021	View substance registered dossier
(7S,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one	837-287-4	1107606-70-1	Active	Intermediate	Joint	Intermediate use only	30-11-2021	View substance registered dossier
(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one	955-019-5	-	Active	Intermediate	Joint	Intermediate use only	22-10-2021	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)	926-987-6	-	Active	Intermediate	Joint	Intermediate use only	13-12-2021	View substance registered dossier

Je zobrazeno 501 - 600 položek z celkového počtu 26 542.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Active	(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	2020	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Cease Manufacture	(4aR,8aR)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one	428-690-2	1668-86-6	2019	View substance registered dossier
NEWCHEM S.P.A.	VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy	Italy	Active	(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one	680-670-4	13649-88-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	(4aS-cis-)-6-benzyl-octahydropyrrolo[3.4-b]pyridine	425-930-8	151213-39-7	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(4E)-2,4-dimethyl-5-(4-methylphenyl)pent-4-enal	951-965-8	1226911-73-4	-	View substance registered dossier
V. MANE FILS	620 route de Grasse 06620 Le Bar sur Loup France	France	Active	(4E)-4-(3,3,4-trimethylcyclopentylidene)butanal	953-704-3	2411191-47-2	-	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one	941-406-6	1391712-50-7	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Active	(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one	941-406-6	1391712-50-7	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(4E)-4-METHYL-5-(4-METHYLPHENYL)-4-PENTENAL	700-748-4	1226911-69-8	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(4E)-5-cyclohexyl-2,4-dimethylpent-4-enal	947-579-4	1449104-34-0	2020	View substance registered dossier
CABB Oy	Kemirantie 1 FI-67701 Kokkola Finland	Finland	Active	(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid	849-166-3	83841-00-3	2020	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa - Attiki Greece	Greece	Active	(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid	849-166-3	83841-00-3	2021	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine	926-346-0	-	-	View substance registered dossier
Sterling Pharma Solutions Ltd	Dudley NE23 7QG Cramlington Northumberland United Kingdom	United Kingdom	No longer Valid	(4R)-4-methyl-1,3-dioxolan-2-one	437-320-9	16606-55-6	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4R)-4-methyl-1,3-dioxolan-2-one	437-320-9	16606-55-6	-	View substance registered dossier
Visolis, B.V.	Urmonderbaan 22 6167 RD Geleen Netherlands	Netherlands	Active	(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	-	View substance registered dossier
-	-	-	-	(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide	809-887-6	1206102-11-5	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	(4R,4'S)-[4,4'-bi-1,3-dioxolane]-2,2'-dione	636-728-6	24690-44-6	-	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(4R,4aS,7aR,12bS)-3-(ethoxycarbonyl)-7-oxo-1,2,3,4,7,7a-hexahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate	955-282-6	2387639-94-1	-	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(4R,4aS,7aR,12bS)-3-methyl-7-oxo-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate	875-213-2	50798-31-7	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol	604-572-8	147128-77-6	-	View substance registered dossier
Isobionics B.V.	Urmonderbaan 22 6167 RD Geleen Netherlands	Netherlands	Active	(4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene	610-461-5	495-61-4	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	(4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one	700-586-4	852212-81-8	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone	848-798-7	272778-12-8	2020	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate	947-346-7	-	2020; 2021	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide	623-314-5	98674-86-3	-	View substance registered dossier
Fine and Performance Chemicals Ltd	Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom	United Kingdom	No longer Valid	(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	2021	View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd	Długosza 67 43-188 Orzesze Poland	Poland	Active	(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	-	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	-	View substance registered dossier
CHEMO BIOSYNTHESIS SRL	VIALE ISONZO, 8 20135 MILANO Italy	Italy	Active	(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)	825-705-8	1235460-56-6	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Active	(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)	940-053-5	-	2017	View substance registered dossier
Hovione Limited	Loughbeg not available Ringaskiddy County Cork Ireland	Ireland	Active	(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)	940-053-5	-	2017	View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos	Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal	Portugal	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	811-441-0	1035654-66-0	-	View substance registered dossier
[Confidential]	-	-	-	(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride	611-780-2	59046-78-5	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid	618-775-4	916439-93-5	-	View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos	Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal	Portugal	Active	(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate	947-931-7	-	-	View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos	Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal	Portugal	Active	(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)	925-915-0	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	165542-15-4	-	View substance registered dossier
-	-	-	-	(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	165542-15-4	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,	824-717-0	403848-30-6	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide	947-800-4	-	-	View substance registered dossier
Sanofi S.R.L.	Viale Luigi Bodio n. 37/b 20158 Milano Italy	Italy	Active	(4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid	443-440-2	150379-92-3	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide	604-558-1	147086-83-7	-	View substance registered dossier
Givaudan France SAS - OR1	55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France	France	Active	(4Z)-hept-4-en-2-yl salicylate	700-488-1	873888-84-7	-	View substance registered dossier
Novartis Ringaskiddy Limited	. . Ringaskiddy County Cork Ireland	Ireland	Cease Manufacture	(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid	700-141-4	117570-53-3	2015	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	(5-bromothiophen-2-yl)-phenylmethanone	608-584-4	31161-46-3	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(5-chloro-2-methoxyphenyl)boronic acid	923-256-3	-	-	View substance registered dossier
Jobachem GmbH	Am Burgberg 13 37586 Dassel Lower Saxony Germany	Germany	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2019	View substance registered dossier
IGM Resins B.V.	Gompenstraat 49 5145 RA Waalwijk Netherlands	Netherlands	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2020	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2015	View substance registered dossier
ARKEMA PHOTOCURES	420 rue d'Estienne d'Orves 92700 Colombes France	France	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
Lankwitzer Lackfabrik GmbH	Haynauer Str. 61-63 12249 Berlin Germany	Germany	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
RAHN NL B.V. (30)	Westplein 11 3016BM Rotterdam Netherlands	Netherlands	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
ARKEMA FRANCE	420 rue d'Estienne d'Orves 92700 COLOMBES France	France	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2018	View substance registered dossier
IGM Resins Ltd	c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom	United Kingdom	No longer Valid	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2021	View substance registered dossier
Labcorp DEVELOPMENT SA 119	Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain	Spain	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
Miwon Europe GmbH	Zeppelinstraße 26 D-47638 Straelen Germany	Germany	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(5E)-3,5-dimethyloct-5-en-4-ol	947-581-5	2209852-19-5	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	(5or8)-aminonaphthalene-2-sulphonic acid	257-269-4	51548-48-2	-	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	(5or8)-aminonaphthalene-2-sulphonic acid	257-269-4	51548-48-2	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate	820-260-6	93603-76-0	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose	815-962-4	1384242-56-1	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose	815-962-4	1384242-56-1	-	View substance registered dossier
[Confidential]	-	-	-	(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol	879-204-4	1373116-05-2	-	View substance registered dossier
[Confidential]	-	-	-	(5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride	874-683-6	1373116-04-1	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one	821-898-8	39931-87-8	2020	View substance registered dossier
[Confidential]	-	-	-	(5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one	260-887-7	57664-96-7	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	(5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate	264-989-2	64643-76-1	-	View substance registered dossier
Alkaloida Chemical Company Zrt.	Kabay Janos 29 H-4440 Tiszavasvari Hungary	Hungary	Active	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	-	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	-	View substance registered dossier
[Confidential]	-	-	-	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	-	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	-	View substance registered dossier
Aesica Pharmaceuticals Limited	Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom	United Kingdom	No longer Valid	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	2021	View substance registered dossier
Macfarlan Smith Limited	Wheatfield Road EH11 2QA Edinburgh United Kingdom	United Kingdom	No longer Valid	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	2021	View substance registered dossier
[Confidential]	-	-	-	(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride	257-924-4	52446-24-9	-	View substance registered dossier
Alcaliber S.A.	Ventalomar 1 45007 Toledo Toledo Spain	Spain	Active	(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol	207-385-6	467-04-9	-	View substance registered dossier
HH Compliance	The Rubicon Centre CIT Campus , Bishopstown T12 Y275 Cork Co Cork Ireland	Ireland	Active	(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol	207-385-6	467-04-9	-	View substance registered dossier
HH Compliance Ltd	Rubicon Building, CIT Campus Bishopstown None Cork Ireland	Ireland	Active	(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol	207-385-6	467-04-9	2022	View substance registered dossier
Macfarlan Smith Limited	Wheatfield Road EH11 2QA Edinburgh United Kingdom	United Kingdom	No longer Valid	(5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one	208-085-8	508-54-3	2021	View substance registered dossier
Macfarlan Smith Limited	Wheatfield Road EH11 2QA Edinburgh United Kingdom	United Kingdom	No longer Valid	(5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one	282-186-5	84116-46-1	2021	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride	245-549-9	23277-43-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Norwegian competent national authority.	-	-	Active	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Cease Manufacture	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	2016	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Cease Manufacture	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	2016	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Portuguese competent national authority.	-	-	Active	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority.	-	-	Active	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	Active	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	-	View substance registered dossier
Archroma UK, Ltd	1 Bartholomew Lane EC2N 2AX London United Kingdom	United Kingdom	No longer Valid	(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	2021	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	(6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride	842-055-0	2356133-42-9	-	View substance registered dossier
[Confidential]	-	-	-	(6-aminohexyl)carbamic acid	205-581-6	143-06-6	-	View substance registered dossier
IB CHEM S.R.L.	VIA E. FERMI 21E 72100 BRINDISI Italy	Italy	Active	(6-aminohexyl)carbamic acid	205-581-6	143-06-6	2018	View substance registered dossier
C.S.B. GmbH	Duesseldorfer Str.113 47809 Krefeld Germany	Germany	Active	(6-aminohexyl)carbamic acid	205-581-6	143-06-6	-	View substance registered dossier
Unimatec Chemicals Europe	Im Technologiepark 1 69469 Weinheim Germany	Germany	Active	(6-aminohexyl)carbamic acid	205-581-6	143-06-6	-	View substance registered dossier
Chemical Inspection & Regulation Service Limited	Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland	Ireland	Active	(6-aminohexyl)carbamic acid	205-581-6	143-06-6	-	View substance registered dossier
W. L. Gore & Associates GmbH	Hermann-Oberth-Strasse 22 85640 Putzbrunn Germany	Germany	Active	(6-aminohexyl)carbamic acid	205-581-6	143-06-6	-	View substance registered dossier
Sterling Pharma Solutions Ltd	Dudley NE23 7QG Cramlington Northumberland United Kingdom	United Kingdom	No longer Valid	(6-Bromo-2-pyridinyl)(4-methylphenyl)methanone	618-079-0	87848-95-1	2021	View substance registered dossier
Glaxo Operations UK	Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom	United Kingdom	No longer Valid	(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate	938-716-9	-	2021	View substance registered dossier
Sanofi Aventis Deutschland GmbH	Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany	Germany	Active	(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one	603-081-6	125-58-6	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	-	View substance registered dossier
Corden Pharma Latina S.p.A.	Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy	Italy	Cease Manufacture	(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	2017	View substance registered dossier
Glaxo Operations UK	Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom	United Kingdom	No longer Valid	(6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	617-560-2	84377-83-3	2021	View substance registered dossier
FRESENIUS KABI iPSUM s.r.l.	Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy	Italy	Active	(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride	827-945-9	107648-80-6	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	2021	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	2018	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	2018	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide	606-382-0	197897-11-3	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	700-301-3	69739-16-8	2021	View substance registered dossier
Alkaloida Chemical Company Zrt.	Kabay Janos 29 H-4440 Tiszavasvari Hungary	Hungary	Active	(6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine	605-428-7	16614-59-8	2020	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	(6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine	605-428-7	16614-59-8	-	View substance registered dossier
Macfarlan Smith Limited	Wheatfield Road EH11 2QA Edinburgh United Kingdom	United Kingdom	No longer Valid	(6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine	605-428-7	16614-59-8	2021	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide	423-260-0	100988-63-4	2021	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	2021	View substance registered dossier
Sanofi Aventis Deutschland GmbH	Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany	Germany	Active	(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid	403-690-5	111298-82-9	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	250-099-1	30246-33-4	2019	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	258-907-4	53994-69-7	2019	View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V.	Alexander Fleminglaan 1 2613 AX Delft Netherlands	Netherlands	Active	(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	-	View substance registered dossier
Sandoz GmbH	Biochemiestr. 10 6250 Kundl Austria	Austria	Cease Manufacture	(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	2020	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	-	View substance registered dossier
AbbVie Logistics B.V.	Zuiderzeelaan 53 8017 JV Zwolle Netherlands	Netherlands	Active	(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one	-	-	2022	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate	949-377-1	-	-	View substance registered dossier
Avara Shannon Pharmaceutical Services Limited	Shannon Industrial Estate V14 FX09 Shannon Clare Ireland	Ireland	Cease Manufacture	(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	2021	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	2018; 2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	-	View substance registered dossier
Avara Shannon Pharmaceutical Services Limited	Shannon Industrial Estate V14 FX09 Shannon Clare Ireland	Ireland	Cease Manufacture	(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	2021	View substance registered dossier
Cambrex Karlskoga AB	Bjorkborns Industriomrade 69185 Karlskoga Sweden	Sweden	Active	(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	2019; 2020	View substance registered dossier
EUROAPI FRANCE	15 rue Traversière 75012 Paris France	France	Active	(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one	615-123-0	7055-53-0	2021; 2022	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	(6β)-6,19-epoxyandrost-4-ene-3,17-dione	433-490-3	6563-83-3	-	View substance registered dossier
Sensient Colors	Oldmedow Road PE30 4LA King's Lynn Norfolk United Kingdom	United Kingdom	No longer Valid	(7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate	807-380-4	377734-55-9	2021	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	-	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	-	View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V.	Alexander Fleminglaan 1 2613 AX Delft Netherlands	Netherlands	Active	(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	2018	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate	642-947-8	415927-29-6	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthrene-3,17-diol	642-948-3	153004-31-0	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(7S,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one	837-287-4	1107606-70-1	-	View substance registered dossier
Industriale Chimica s.r.l.	via E.H. Grieg, 13 21074 Saronno (VA) Italy	Italy	Active	(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one	955-019-5	-	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)	926-987-6	-	2021	View substance registered dossier

Je zobrazeno 501 - 600 položek z celkového počtu 26 542.

Údaje pocházejí z registračních dokumentací předložených agentuře ECHA do data uvedeného jako datum poslední aktualizace. Celkové množstevní rozmezí je stanoveno na základě všech dokumentací, přičemž se však nezahrnují dva typy údajů. Množství, která jsou uváděna jako důvěrné informace, a množství použitá jako meziprodukt k výrobě jiných chemických látek. Celkové množstevní rozmezí, které je zveřejněno, tudíž nemusí nutně odpovídat zaregistrovanému množstevnímu rozmezí (zaregistrovaným množstevním rozmezím).

Upozorňujeme, že některé informace o registrovaných látkách mohou patřit třetím stranám. Pro používání takovýchto informací tudíž může být nezbytný předchozí souhlas třetí strany, která je vlastní. Více k tomuto tématu naleznete v právním upozornění.

Vyhledávání údajů o chemických vlastnostech

Upozorňujeme, že informace o chemických vlastnostech registrovaných látek jsou přímo dostupné na portálu eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.

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