Registration Dossier
Registration Dossier
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EC number: 304-661-9 | CAS number: 94277-77-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The 3-h EC50 and EC20 values are >1000 mg/L as observed in a respiration inhibition study with activated sludge from laboratory wastewater treatment plants fed with municipal and synthetic wastewater. The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
The toxicity of the substance to microorganisms was investigated in an activated sludge respiration inhibition study according to EU guideline C.11 and in compliance with GLP criteria (BASF, 1998).
In this limit test activated sludge from laboratory wastewater treatment plants fed with municipal and synthetic wastewater was exposed to nominal test substance concentrations of 0 (control) and 1000 mg/L for 30 minutes. Test concentrations were not analytically verified. The effects on microorganisms was determined by measuring total respiration rates and comparing these to an unexposed control. No significant inhibition of respiration rates was observed at any of the concentrations tested. Based on these findings, both the 3 -h EC50 and EC20 values were determined at >1000 mg/L.
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