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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

No OECD guideline study on carcinogenicity exists for BeO. A total of 16 studies were found to be of relevance for assessing the carcinogenic potential of BeO. However, only 2 of these (Sanders and Barna) were found reliable. The remaining studies were not found to be sufficient for assessment of carcinogenic potential of BeO

Key value for chemical safety assessment

Justification for classification or non-classification

Additional information

The majority of studies on BeO and cancer have focused on tumor formation in the skeleton or lungs. The results from these studies have generally been mixed. Early studies often saw a significant level of osteosarcomas while tumors in the lung was rarely seen. Although the majority of these studies were not considered reliable, due to limited reporting and occasionally irrelevant administration methods (human relevance), there seem to be an increased incidence of osteosarcomas in exposed animals, particularly rabbits. Of the studies that were found reliable (Sanders and Barna) there was no clear evidence of carcinogenicity.