EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 17 září 2021. Database contains 4621 unique substances/entries.
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203-770-8
110-46-3
Flam. Liq. 2; Acute Tox. 4
412-170-7
83623-61-4
STOT RE 2; Eye Dam. 1; Skin Sens. 1
430-460-1
133636-82-5
Skin Corr. 1B; Skin Sens. 1
-
-
Skin Sens. 1
432-360-3
105813-13-6
Acute Tox. 4; Skin Sens. 1
406-030-4
105812-81-5
Acute Tox. 4; Eye Dam. 1
214-619-0
1166-46-7
Carc. 2; Acute Tox. 4; STOT SE 2
425-230-2
16610-63-2
Skin Corr. 1B
256-032-2
42978-66-5
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
-
-
Skin Irrit. 2
427-580-1
2135337-60-7
Skin Irrit. 2
418-530-1
79200-56-9
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
411-000-9
125224-62-6
Skin Sens. 1
412-670-5
54275-93-3
Resp. Sens. 1
412-800-0
76109-32-5
Resp. Sens. 1
426-200-1
172015-79-1
STOT RE 1; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
420-560-3
79617-97-3
Eye Dam. 1
220-384-5
2746-19-2
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
426-740-8
-
Acute Tox. 4; Eye Dam. 1
407-240-9
159604-94-1
Skin Sens. 1
443-840-7
4084-38-2
Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
439-360-2
142877-45-0
Skin Irrit. 2; Eye Dam. 1
430-620-0
76145-91-0
STOT RE 2; Skin Sens. 1
433-520-5
82911-69-1
Acute Tox. 4; Skin Sens. 1
430-910-7
13335-71-2
Acute Tox. 4; Eye Dam. 1
404-940-6
86608-70-0
Acute Tox. 4; Eye Dam. 1; STOT RE 2
417-410-4
61807-67-8
Acute Tox. 4; Skin Corr. 1A; Skin Sens. 1
444-800-1
141645-23-0
Flam. Liq. 3; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
429-740-6
40722-80-3
Carc. 1B; Muta. 1B; STOT RE 2; Skin Sens. 1
284-351-7
84852-39-1
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
287-470-2
85508-45-8
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
440-620-2
920-36-5
Water-react. 1; Pyr. Liq. 1; Skin Corr. 1A; STOT SE 3
420-370-0
6485-67-2
Eye Irrit. 2; Skin Sens. 1
-
-
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
433-820-6
118058-74-5
Eye Irrit. 2
408-050-9
76855-69-1
Eye Irrit. 2; Skin Sens. 1
425-260-6
244634-31-9
STOT RE 2; Eye Dam. 1; Skin Sens. 1
201-501-9
83-79-4
Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
-
1417782-03-6
Skin Sens. 1
443-560-5
88784-33-2
Eye Irrit. 2
427-200-4
76646-91-8
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
422-240-9
166596-68-5
Eye Dam. 1; Skin Sens. 1
428-230-0
79568-06-2
STOT RE 2
222-048-3
3327-22-8
Carc. 2
423-290-4
66938-41-8
Muta. 2
420-380-5
136465-81-1
Acute Tox. 4; Eye Dam. 1
444-350-6
133413-70-4
Eye Irrit. 2
430-230-0
136522-17-3
Acute Tox. 4
419-790-7
4229-69-0
Skin Sens. 1
422-960-3
178233-72-2
Acute Tox. 4; STOT RE 2
406-010-5
88918-84-7
Eye Dam. 1; Skin Sens. 1
247-162-0
25646-77-9
Acute Tox. 3; STOT RE 2; Skin Sens. 1
405-020-7
105024-66-6
Repr. 1B
406-090-1
81880-96-8
Muta. 2; Acute Tox. 3; STOT RE 1; Skin Sens. 1
420-450-5
86552-32-1
Carc. 2; Eye Dam. 1
428-690-2
1668-86-6
Acute Tox. 4; Eye Irrit. 2
425-930-8
151213-39-7
Skin Corr. 1B; Acute Tox. 4; STOT RE 2
692-456-8
688046-61-9
Carc. 2
402-060-7
108225-03-2
Carc. 1B; Eye Dam. 1
423-260-0
100988-63-4
Muta. 2; Skin Sens. 1
433-490-3
6563-83-3
Skin Sens. 1
406-790-7
26116-56-3
Eye Dam. 1
244-445-0
21564-17-0
Acute Tox. 2; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
401-450-4
95154-01-1
Skin Sens. 1
402-460-1
-
Skin Irrit. 2; Skin Sens. 1
616-221-6
7541-49-3
Skin Irrit. 2
204-647-1
123-73-9
Flam. Liq. 2; Muta. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
227-678-2
5932-68-3
Skin Sens. 1A
421-370-3
3681-73-0
Skin Irrit. 2
410-980-5
112704-51-5
Eye Irrit. 2; Skin Sens. 1
426-330-9
177964-68-0
Eye Irrit. 2; Skin Sens. 1
428-010-4
82413-20-5
Carc. 2; Repr. 1B; Skin Sens. 1
429-900-5
82356-51-2
Skin Sens. 1
210-855-3
624-64-6
Flam. Gas 1; Press. Gas
406-100-4
94097-88-8
Skin Sens. 1
423-240-1
125474-34-2
Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
MEXORYL SX; SX 32
410-960-6
92761-26-7
Eye Dam. 1
418-960-8
-
Skin Corr. 1B; Skin Sens. 1
402-370-2
149057-70-5
Flam. Liq. 3; Eye Dam. 1
284-348-0
84852-36-8
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
285-909-2
85166-19-4
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
287-471-8
85508-46-9
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
287-592-6
85551-28-6
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
284-347-5
84852-35-7
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
401-500-5
118658-99-4
Carc. 1B
422-200-0
178277-55-9
Skin Corr. 1B; Acute Tox. 4
401-840-4
55845-90-4
Eye Dam. 1
415-110-8
54417-53-7
Acute Tox. 4
444-320-2
-
Acute Tox. 4
407-960-3
94050-90-5
Eye Dam. 1
-
178961-20-1
Skin Sens. 1
430-560-5
180637-89-2
Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
430-760-2
219861-18-4
Acute Tox. 4; Skin Sens. 1
226-908-9
5543-58-8
Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
422-390-5
143322-57-0
Repr. 2; STOT RE 1; Acute Tox. 4; Skin Sens. 1
238-967-8
14898-79-4
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
227-813-5
5989-27-5
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1B; Asp. Tox. 1
236-232-6
13250-12-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
418-570-8
25383-07-7
Repr. 2
-
-
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
447-860-7
144177-62-8
Repr. 2; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
421-830-3
49805-30-3
Acute Tox. 4; Skin Sens. 1
431-210-4
50905-10-7
Eye Dam. 1
430-780-1
103146-25-4
Acute Tox. 4; Skin Sens. 1
-
-
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
701-225-3
1101132-67-5
Carc. 2; Repr. 2; STOT RE 2
811-718-6
86347-14-0
Acute Tox. 2; STOT SE 3; STOT SE 1; STOT RE 1
420-610-4
36394-75-9
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
421-810-4
194602-27-2
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
410-860-2
79815-20-6
Repr. 2; STOT RE 2; Skin Sens. 1
411-150-5
29617-66-1
Acute Tox. 4; Skin Corr. 1A
434-990-4
7331-52-4
Skin Sens. 1
430-900-2
192725-50-1
Eye Dam. 1
430-770-7
128173-52-4
Acute Tox. 4; Skin Sens. 1
226-907-3
5543-57-7
Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
-
-
Acute Tox. 4; Skin Sens. 1
224-168-1
4221-99-2
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
412-470-8
73246-45-4
Flam. Liq. 3; STOT RE 2; Eye Irrit. 2
414-600-9
149182-72-9
Acute Tox. 4
227-815-6
5989-54-8
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
208-164-7
513-49-5
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
430-300-0
76932-17-7
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
441-070-6
61826-76-4
Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
601-696-4
120298-38-6
Skin Sens. 1
BENACTIVE GOLDEN YELLOW CN-GL; C.I. REACTIVE YELLOW 178; KAYACELON REACT GOLDEN YELLOW CN-GL; SOMAZIN GOLDEN YELLOW CN-GL
404-250-5
115099-55-3
Skin Sens. 1
CARTASOL TUERKIS K-ZBL KONC.; CARTASOL TURQUOISE K-JD 2336; CARTASOL TURQUOISE K-JD 2336 CONC.; CARTASOL TURQUOISE K-ZBL CONC.; CARTASOL TÜRKIS K-ZBL FLÜSSIG; CARTASOL TÜRKIS K-ZBL KONZ.; TURQUOISE CARTASOL K-JD 2336 CONC.
401-260-1
118800-27-4
Eye Irrit. 2
C.I. REAKTIV-BLAU 216; KAYACELON REACT BLUE CN-BL; KAYACELON REAKT-BLAU CN-BL; UBCNBL
404-670-9
89797-01-3
Skin Sens. 1
424-740-2
138271-16-6
Acute Tox. 4; Eye Dam. 1
233-195-8
10061-01-5
Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; Asp. Tox. 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
410-780-8
-
Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
426-210-6
120086-58-0
Skin Corr. 1B
430-100-3
86978-24-7
Acute Tox. 4
227-633-7
5912-86-7
Skin Sens. 1A
431-520-1
64485-90-1
Flam. Sol. 1; Carc. 2
209-673-7
590-18-1
Flam. Gas 1; Press. Gas
204-015-5
112-90-3
Acute Tox. 4; Asp. Tox. 1; STOT SE 3; STOT RE 2; Skin Corr. 1B
600-853-4
107898-54-4
Skin Irrit. 2
281-291-3
83918-57-4
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
281-291-3
83918-57-4
Acute Tox. 4; Skin Sens. 1
205-341-0
138-86-3;7705-14-8
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
205-341-0
138-86-3;7705-14-8
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
430-730-9
-
Eye Dam. 1
-
99095-19-9
Acute Tox. 4; Skin Sens. 1
PAYLEAN; RACTOPAMINE HYDROCHLORIDE
415-170-5
90274-24-1
Acute Tox. 4; Skin Sens. 1
419-600-2
99199-90-3
Skin Sens. 1
201-158-5
15892-23-6;78-92-2
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
201-158-5
15892-23-6;78-92-2
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
BRL 44742
415-550-0
109887-53-8
Acute Tox. 4; Eye Dam. 1
419-290-9
-
Skin Sens. 1
407-840-0
100011-37-8
Acute Tox. 4; Eye Dam. 1
407-880-9
117549-13-0
Acute Tox. 4
204-528-4
122-20-3
Eye Irrit. 2
405-840-5
110866-35-8
Skin Sens. 1
219-306-2
2407-94-5
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
219-306-2
2407-94-5
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
203-820-9
110-97-4
Eye Irrit. 2
430-250-1
406-58-6
Flam. Liq. 2
200-756-3
71-55-6
Acute Tox. 4
201-191-5
79-27-6
Acute Tox. 2; Eye Irrit. 2
201-197-8
79-34-5
Acute Tox. 2; Acute Tox. 1
201-166-9
79-00-5
Carc. 2; Acute Tox. 4
419-430-9
56533-00-7
Acute Tox. 4; STOT RE 2; Skin Corr. 1B
424-980-8
22288-41-1
Flam. Liq. 2; Org. Perox. D; Skin Irrit. 2; Skin Sens. 1
209-854-0
594-72-9
Acute Tox. 3
200-863-5
75-34-3
Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
200-864-0
75-35-4
Flam. Liq. 1; Carc. 2; Acute Tox. 4
209-253-3
563-58-6
Flam. Liq. 2; Acute Tox. 3
203-310-6
105-57-7
Flam. Liq. 2; Eye Irrit. 2; Skin Irrit. 2
413-740-8
1132-95-2
Skin Corr. 1B
208-589-8
534-15-6
Flam. Liq. 2
-
4482-55-7
Skin Irrit. 2
442-850-9
114772-40-6
Skin Sens. 1
246-147-6
24307-26-4
Acute Tox. 4
431-610-9
68860-54-8
Org. Perox. D; Skin Sens. 1
200-629-2
66-71-7
Acute Tox. 3
210-168-9
608-73-1
Carc. 2; Acute Tox. 3; Acute Tox. 4
212-230-0
771-29-9
Org. Perox. D; Acute Tox. 4; Skin Corr. 1B
414-270-6
41959-35-7
Acute Tox. 4
204-340-2
119-64-2
Eye Irrit. 2; Skin Irrit. 2
-
6202-15-9
Expl. 1.1; Acute Tox. 4
212-557-9
826-62-0
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
226-247-6
5333-84-6
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
222-323-8
3425-89-6
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
247-830-1
26590-20-5
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
201-605-4
85-43-8
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
202-486-1
96-18-4
Carc. 1B; Repr. 1B; Acute Tox. 4
206-022-9
288-88-0
Repr. 1B; Acute Tox. 4; Eye Irrit. 2
204-428-0
120-82-1
Acute Tox. 4; Skin Irrit. 2
202-436-9
95-63-6
Flam. Liq. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
221-695-9
3194-55-6
Repr. 2; Lact.
271-093-5
68515-50-4
Repr. 1B
284-032-2
84777-06-0
Repr. 1B
276-158-1
71888-89-6
Repr. 1B
271-084-6
68515-42-4
Repr. 1B
220-120-9
2634-33-5
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
203-977-3
112-49-2
Repr. 1B
417-610-1
155522-09-1
Skin Sens. 1
3,4-DIACETOXY-1-BUTENE
421-720-5
18085-02-4
Acute Tox. 4
202-479-3
96-12-8
Carc. 1B; Muta. 1B; Repr. 1A; Acute Tox. 3; STOT RE 2
203-444-5
106-93-4
Carc. 1B; Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2

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