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Survey finds laboratory capacity available for conducting EOGRTS
ECHA/NI/16/01
ECHA commissioned a study on global laboratory capacities to conduct extended one-generation reproductive toxicity studies (EOGRTS).
Helsinki, 13 January 2016 - In total, 22 laboratories were identified as capable to conduct these studies. It is estimated that for 2016, 2018 and 2020, these laboratories could deliver the following ranges of EOGRTS with basic study design: 88-114, 94-122 and 101-131 respectively. Regarding full study designs, the ranges are 44-57, 49-63 and 61-79 for the respective years.
Compared with a similar study in 2012, the global laboratory capacity to conduct EOGRTS has increased. The study was triggered by the recent change in the REACH information requirements where EOGRTS replaced the previous two-generation reproductive toxicity study.
ECHA's endpoint specific guidance on reproductive toxicity was updated accordingly. It describes the criteria for the study design of EOGRTS.